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Back to QuestionsGeneral

In general, what is the onset of action of an antihypertensive and an antidepressant?

The onset of action for most anti-hypertensive medications typically occurs within a few weeks. Adjustments to the medication based on blood pressure targets are usually made around four weeks after starting the treatment or changing the dose. Blood pressure readings taken twice, twice a day (totaling four readings in a day), over seven days help determine the effectiveness of the medication. If the targets are met, the same dose can be continued. However, if the targets are not met, a treatment adjustment may be necessary. In general, another four weeks are typically waited before reassessing blood pressure readings. For antidepressant medications, the onset of action is also expected within a few weeks. A medication should show some level of effectiveness after two weeks of treatment, known as the "response." The maximum effectiveness, known as "remission," is usually reached after six to eight weeks of treatment. If the treatment goals in terms of response and remission are not met, it is important to consult with a pharmacist or doctor for a potential adjustment. The presence of adverse effects may require prompt communication with a healthcare provider to manage them effectively. If these adverse effects become too bothersome, the healthcare provider can be contacted to find a suitable solution.

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