Factors or medications that can increase the risk of an ectopic pregnancy include a history of pelvic inflammatory disease, previous ectopic pregnancy, history of abortion, and smoking. The use of an intrauterine device (IUD) as a contraceptive method has also been linked to an increased risk. Symptoms of an ectopic pregnancy can vary but may include vaginal bleeding, vaginal discharge, cramps or pain in the lower abdomen, sweating, dizziness, or fainting. Ectopic pregnancy is a medical emergency and requires immediate attention. There are resources available, such as a guide produced by McGill University, for women undergoing treatment with methotrexate for this condition, explaining what an ectopic pregnancy is, how methotrexate works to treat it, proper administration of the medication, and when to seek emergency care.