Yes, you can take Tylenol Cold Day/Night while taking sertraline. Just make sure to follow the recommended dosage on the packaging. However, if you have high blood pressure or if you are pregnant, it is best to avoid Tylenol Day/Night and stick to plain acetaminophen. Tylenol Night contains an ingredient to help you sleep, so be cautious if you are also taking Ativan, as they both can cause drowsiness. Start with just Tylenol Night at bedtime to see how it affects you before combining it with Ativan. You may find that you don't even need the Ativan during this time.
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