Yes, irritation at the application site is a possible side effect of the Evra patch. It is recommended to apply the patches in different areas to minimize this possible side effect. If the irritation persists or is intolerable, it is advisable to consult with a pharmacist. There are other contraceptive options available, and a pharmacist can help discuss alternative options with you to present to your doctor. In the meantime, avoid reapplying the patch to a region of the skin that is already irritated. For irritations, you can apply a cream containing 1% hydrocortisone (available over the counter) and a fragrance-free moisturizer as often as desired throughout the day, especially when it feels itchy.
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