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How much Advil and Tylenol can I take for a toothache?

soon. For a 37-year-old man with no known allergies to medication, the maximum recommended daily dose of Tylenol (acetaminophen) is 4000mg, or 8 tablets of 500mg or 12 tablets of 325mg. The maximum over-the-counter dose of Advil (ibuprofen) is 1200mg per day (6 x 200mg tablets or 3 x 400mg tablets). However, with a prescription, higher doses may be used depending on the treatment indication. Be aware of the potential risks associated with ibuprofen, such as gastric issues and increased blood pressure. If you are taking medication for a toothache, be sure to consult your dentist if there is no improvement soon.