Yes, it is possible to take Glumetza 1000mg at bedtime instead of the 500mg in the morning and 500mg at bedtime. Taking the medication with food may help reduce stomach irritation and nausea. If switching the time of day or taking it with food does not improve your symptoms, it is possible that you may not tolerate the medication well. In that case, it is important to consult with a pharmacist or your doctor to explore other treatment options and possibly identify any other underlying medical conditions that could be causing the nausea.
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