If you are experiencing a skin reaction to poison ivy, it is important to clean the affected area thoroughly with soap and water to remove any traces of the plant resin. Avoid scratching the blisters as they could become infected. Applying cold compresses and hydrocortisone cream can help reduce the itching and inflammation. It is also recommended to avoid exposing the affected area to sunlight. If the reaction is severe, you may consider taking an antihistamine like Benadryl to help with the itching. It may take a week or more for the skin to fully heal, so be patient and avoid scratching the affected area. If the reaction worsens, covers a large portion of your body, or shows signs of infection, it is best to consult a doctor.