If you are experiencing sciatic nerve pain during pregnancy, it is important to avoid certain medications and opt for non-pharmacological methods to alleviate the discomfort. Some options include light exercise such as swimming, physiotherapy, massage, and acupuncture. If the pain persists, you can consider taking acetaminophen (Tylenol) under the guidance of a healthcare provider. It is important to avoid anti-inflammatory medications like ibuprofen during pregnancy. Additionally, you may ask a pharmacist about a cream containing triethanolamine salicylate that could be used occasionally on a small area for pain relief.