Yes, taking venlafaxine (Effexor) for several years should not typically make a person feel more tired or drowsy. These side effects are usually more noticeable at the beginning of treatment and tend to lessen over time. If these symptoms persist after several months, it may be a sign that the medication is not working effectively or that the dosage is too low. It is important to consult with a healthcare provider in this case. Additionally, missing a dose of venlafaxine can cause withdrawal symptoms such as dizziness and insomnia, especially if the usual dosage is relatively high. If you have any further questions or concerns, it is recommended to speak with a healthcare professional.