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Can I open the Fluconazole tablet instead of swallowing it whole?

Yes, you can open the Fluconazole capsule and sprinkle the contents on applesauce or yogurt to take it. You can also dissolve it in water, but make sure to rinse the glass with water and drink all the contents to ensure you get the full dose. If you prefer, you could ask the pharmacy for the medication in tablet form.