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Can the removal of the Mirena IUD and taking the Jencycla pill cause menstrual-like cramps and spotting?

Yes, it is possible for the removal of a Mirena IUD and starting a new birth control pill to cause menstrual-like cramps and spotting. These side effects are common when starting a new method of contraception and usually resolve on their own. It's important to continue taking the new pill at the same time every day. If the symptoms persist for more than a month or become more intense, it's advisable to consult a healthcare provider for further evaluation.