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Do I have to resume the prednisone if I vomited about 1 hour after having taken it to relieve the swelling of my throat due to a streptococcus and mononucleosis?

I advise you to take the medication again and contact the pharmacy to get an extension of treatment. It is possible that the medication has had time to be absorbed, but we cannot be sure. The wisest thing is to take a new dose, as your situation is rather serious and a delay in healing could have unfortunate consequences.