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Do you know of any cream that could help heal an irritation at the entrance of the vagina/perineum following sexual intercourse?

It is not recommended to use cream for irritation near the entrance of the vagina/perineum after sexual intercourse as it may disrupt the vaginal flora. However, if the symptoms persist for more than 5 days, you could try using a vaginal and vulvar moisturizer like Replens™.