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Does taking azithromycin for a chlamydia infection affect the effectiveness of birth control pills?

Taking azithromycin for a chlamydia infection does not affect the effectiveness of your birth control pill. However, if you experience diarrhea during the treatment, it could potentially decrease the absorption of your pill. It is important to be aware that one day of diarrhea is equivalent to missing one pill. This applies to all types of diarrhea, whether they are caused by antibiotics or other factors such as stomach bugs.