It is possible for the Mirena IUD to cause acne, fatigue, and shortness of breath as side effects, just like other hormonal contraceptives. Some women may also experience abdominal pain, especially after the insertion of the IUD. If these symptoms persist or become unbearable, it is recommended to consult a healthcare provider. It is important to monitor how your body adjusts to the IUD over time, as some side effects may improve with continued use.