For 2 days I have had pain in my anus and there is a bump. Sitting is uncomfortable, should I wipe?

Yes, irritation in the anal area can be treated with an ointment like Anusol Plus applied twice a day and after each bowel movement. It is also recommended to use unscented wet wipes or a clean towel with water for hygiene. Avoid sitting on the toilet seat for too long and consult with a pharmacist for personalized advice and follow-up.