. Hello, typically we should see a significant improvement in your symptoms within 48 hours (less whitish secretions and reduced itching). However, it may take several days for the symptoms to completely resolve, as the bacterial flora has been disrupted by the infection. You may still experience some local irritation (redness, etc.) and itching, but the best indicator that your infection is being treated successfully is the disappearance of any odor and whitish secretions.