Hello, normally we should notice a marked improvement in symptoms within 48 hours, including a decrease in whitish secretions and an improvement in itching. However, complete resolution of symptoms may take several days, as the bacterial flora is disrupted by the infection and some symptoms such as local irritation (redness, etc.) and itching may persist. The best way to know if your infection is being treated properly is the disappearance of the odor and whitish secretions.