It is important to avoid taking Tylenol Sinus if you are already taking Venlafaxine, as there may be interactions between the two medications. Additionally, it is recommended to focus on nasal hygiene and drink plenty of fluids to help alleviate symptoms like cough and nasal congestion. Using products like Aquaphor or Vaseline can help soothe sensitive areas around the nose and lips due to frequent blowing. If tissues are too harsh, using unscented wet wipes may be a gentler option for blowing your nose.