I am taking Wellbutrin (bupropion), Paxil (paroxetine), hydrochlorothiazide and I have a prolonged QT. Are there any natural products that I can't take? Like echinacea, valerian, etc.?

. It is known that some natural products can increase the concentrations of the drugs you are taking in the blood, potentially increasing the risk of QT prolongation. Valerian may increase the levels of paxil, so I would advise avoiding this natural product. Echinacea appears to be safe in your case. Additionally, natural products that can cause dehydration or decrease potassium in the blood should be avoided, as this can further lengthen your QT. I recommend consulting with your pharmacist before consuming any natural product.