If you are experiencing difficulties with constipation and have tried different medications without success, it is recommended to focus on non-pharmacological measures such as increasing fiber intake, staying active, drinking enough water, maintaining a regular schedule, and creating a favorable environment. If these measures do not help alleviate your symptoms, it is important to consult a doctor for further evaluation, especially if you experience severe pain, blood in your stool, significant bloating, weight loss, or other concerning symptoms. Don't hesitate to seek medical advice if you have any additional questions.