To reduce throat irritation and chest pain associated with coughing, it is recommended to reduce the amount of mucus in your throat. You can try using a product like Sinus Rinse™ or Hydrasense™ to help with this. Additionally, honey or a cough syrup with DM may help soothe throat irritation. Chest pain should improve once the cough is under control. If the cough persists for more than 3 weeks after the first symptoms or if you develop a fever, it is advisable to consult a doctor.