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"I have a huge toothache, Advil doesn't seem to be working?"

The most effective medications for tooth pain are Advil and Tylenol, which can be taken together. However, if you have a severe toothache that is not responding to medication, it is important to see a dentist as soon as possible to address the issue before it gets worse. It is recommended to contact a dentist to try to schedule an appointment sooner rather than later.