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I have a swelling behind my ear that is painful. It has been going on for 2-3 days.

It is advised to consult a doctor if the condition does not improve within a few days of using Polysporin. If there is worsening or no improvement in symptoms after following the recommended care, it may be necessary to consider oral antibiotics. It is important to monitor the level of pain and the progression of the swelling to determine the appropriate next steps.