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I have lupus and I take several medications. I wonder if any of them can cause anxiety (Plaquenil, Aspirin, Pantoloc, mycophenolate and trazodone)?

Good morning. It is possible that your anxiety symptoms may be related to your medication, particularly mycophenolate or hydroxychloroquine (Plaquenil). However, it is not safe to stop taking your medication without consulting your doctor or pharmacist. I suggest that you make an appointment with your doctor or pharmacist as soon as possible.