Yes, you can take Naproxen for menstrual pain. Anti-inflammatory medications like Naproxen and over-the-counter Ibuprofen (Advil/Motrin) are usually more effective than Acetaminophen for menstrual pain. However, there are certain contraindications to using anti-inflammatories. If your health has changed since you were prescribed Naproxen or if you are taking new medications, it is advisable to consult your pharmacist before taking Naproxen again. Be sure not to exceed the prescribed dose and do not combine it with any other anti-inflammatory, whether taken orally or applied as a gel on the skin (Voltaren).