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I have to put Polysporin on a wound (recommended by a doctor), but I just had a hives-type reaction. What can I replace this ointment with?

You could replace the Polysporin with Bactroban, an over-the-counter antibiotic that you can ask for at the pharmacy. If the itching persists, it is recommended to have the wound evaluated by a doctor or nurse. Some pharmacies offer services with a nurse by appointment.