It is common for antidepressants, like Effexor, to affect libido and sexual function. It may be helpful to try creating romantic and intimate moments with your partner to help reignite desire. Additionally, there are gadgets and products available that may assist in improving sexual function. If these options do not work, speaking with your doctor about potentially switching to a different antidepressant with less impact on sexual function, like bupropion, could be considered. This should be discussed with your healthcare provider to determine the best course of action.