If over-the-counter creams like Preparation H are not effectively treating your hemorrhoids, it may be necessary to consult a healthcare professional for a more suitable product. They may recommend additional measures such as increasing fiber intake to prevent constipation, using certain laxatives, and incorporating sitz baths into your routine to reduce irritation and pressure on the affected area. Additionally, the use of a cream containing hydrocortisone after the sitz bath may also be beneficial. It is important to seek proper medical advice for appropriate treatment.