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I was wondering if it was dangerous to take Advil Cold and Sinus while I am taking Trintellix.

It is not recommended to take Advil Cold and Sinus with Trintellix as it can increase the risk of side effects such as tremors, anxiety, insomnia, and stomach irritation. It is best to use Tylenol for pain relief instead. You can also use throat lozenges like Halls or Fisherman's Friend for local relief. It is important to stay hydrated by drinking plenty of fluids and to practice nasal hygiene with saline solutions like Hydrasense or Sinus Rinse.