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Is it common to combine 2 antidepressants?

It is not uncommon to combine two antidepressants, with Bupropion often being used in addition to a first antidepressant for lack of energy. The duration of treatment varies, with some people able to stop taking antidepressants once their condition has stabilized. It is important to discuss any changes in medication with your healthcare team when you feel ready, in order to plan a gradual decrease. It is possible to stop taking antidepressants after the condition has stabilized.