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Is it normal for my arm to swell and be very painful 12 hours after my vaccination?

Yes, it is normal to experience swelling and pain in your arm after getting a vaccine. You can try taking Ibuprofen for pain and inflammation, applying cold compresses, and cleaning with alcohol to help reduce swelling. If there is no improvement after 48 hours, or if you experience difficulty breathing, palpitations, or swelling of the lips, it is important to seek medical attention immediately.