Is it normal that after 2 doses of Trazodone 50mg I still do not feel the effects?

It is normal for it to take some time before feeling the effects of Trazodone. Some people may experience immediate effects, but it can take several days to up to 6 weeks to reach its full effectiveness. As for weight gain, studies suggest that around 1 to 5% of people taking Trazodone may experience weight gain as a side effect, which is lower compared to some other antidepressants. This risk is dose-dependent, meaning lower doses like the one prescribed to you are less likely to cause weight gain compared to higher doses.