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Is it normal to have vaginal itching after taking penicillin for a week?

Yes, it is possible to combine an oral treatment with a cream for vaginal itching caused by taking antibiotics. You can use a Canesten cream for a few days to treat a yeast infection. Additionally, you can also take a fluconazole capsule orally to help with the infection. Make sure to consult with a pharmacist for the appropriate treatment option.