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Is it possible to have eczema in this area? The moisturizing cream doesn't seem to be effective, my breasts itch a lot.

Yes, it is possible to develop eczema in that area. If the moisturizing cream is not effective and your skin is itching a lot, it may be helpful to consult with a pharmacist for personalized advice. They can recommend different treatments or products that may be more effective for your specific needs.