"Minocycline for 2 months for acne and no difference..."

Based on the information provided, it seems that after 2 months of taking minocycline for acne with no improvement, it may be time to consider other treatment options. It would be best to consult with your doctor to discuss alternative options that may be more effective. Your pharmacist can also be a helpful resource in discussing potential next steps with your doctor. There are various topical and oral treatments available that may be more beneficial than minocycline. Good luck in finding a solution for your acne.