Since last June I have been taking 50mg of Zoloft while eating in the evening. It helps, but my tongue is irritated and burning. Is this normal?

Yes, it is possible for Zoloft to cause dry mouth as a side effect, which can lead to irritation and a burning sensation on the tongue. This side effect affects about 1 in 6 people who take Zoloft. To relieve this discomfort, it is recommended to increase saliva production. There are different products available, some of which may require a prescription, that can help with dry mouth. Additionally, reducing the dosage of the medication with the guidance of a healthcare professional may also help alleviate this side effect. It is recommended to consult with a pharmacist to explore options for increasing mouth hydration, such as products containing Xylitol that can be found in pharmacies.