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What can I put on a blister under the foot?

To protect a blister on the foot, you can cover it with a bandage to prevent friction and popping. To reduce pain, you can take acetaminophen (such as Tylenol) or ibuprofen (such as Advil) if there are no contraindications. Applying ice wrapped in a damp cloth for 10 to 15 minutes as needed throughout the day can also help. If the blister becomes more red, swollen, or painful, it is best to seek medical advice for further evaluation.