It is important to be aware of the potential risks associated with combining drugs like Speed and Ecstasy with medications. Ecstasy can increase the risk of dehydration, which can be exacerbated by certain antibiotics causing diarrhea. It is known that MDMA can make a person less responsive to thirst signals, which, combined with dehydration from diarrhea, can lead to permanent kidney damage. Additionally, the effects of different pills can vary greatly due to the fact that MDMA can be mixed with various substances. It is important to remember that the possession, trafficking, production, and import/export of MDMA are illegal. If you notice someone under the influence of Ecstasy, remind them to stay properly hydrated and to urinate promptly to avoid more serious consequences.