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What should he do, he has an appointment with his doctor on April 12, should he go to the emergency room or can he wait until April 12?

It is always recommended to consult a healthcare professional if there is any concern about a medical issue. In this case, since the person has an appointment with their doctor on a specific date, it would be best to follow up with their doctor before taking any action. If there are urgent symptoms or worsening of the condition before the appointment date, it may be necessary to seek immediate medical attention at the emergency room.