When should I take quetiapine so that it doesn't make me sleepy during the day?

It is recommended to try taking half a tablet at dinner to see if it is effective at night without causing drowsiness in the morning. Alternatively, you could try taking one tablet between the afternoon and dinner time. It may be a process of trial and error to find the best timing for taking the medication. Once you have found the optimal timing for one tablet, it may be best to stick with that before considering taking two tablets. Your pharmacist will have more information and be able to personalize a treatment plan for you.