Yes, antidepressants can sometimes cause numbness as a side effect. If you are experiencing swelling and numbness in your hand and arm, it is important to consider other possible causes as well. It could be related to your medication, but it is also possible that it is due to how you position your arm while sleeping, which can irritate the nerves. If the sensation decreases during the day and there are no other concerning symptoms, there may not be a need to worry.
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