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Can changing the time of day I take Zoloft cause headaches?

Yes, changing the time of taking Zoloft can potentially cause headaches. It is recommended to not take an extra dose if you have already taken one earlier in the day. If you want to switch the time you take Zoloft, it is suggested to gradually transition by taking the next dose later the following day and then in the evening the day after to avoid potential side effects like headaches.