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Can I take 2 tablets of Naproxen 220mg in one dose if my prescription for 500mg is no longer valid?

It is not recommended to take 2 tablets of Naproxen 220mg in one dose if your prescription for 500mg is no longer valid. It is best to follow the instructions on the product label and take only 1 tablet at a time. It may be helpful to combine it with Tylenol Extra-Strength until you can get your prescription renewed. It is important to consult with your pharmacist for guidance on how to proceed to have your medication prescribed by your doctor.