Yes, it is recommended to separate the intake of Synthroid and iron supplements. Taking them together can reduce the effectiveness of your Synthroid. You can take the iron supplements on an empty stomach, 1 hour before a meal, or 2 hours after a meal. If the iron causes digestive discomfort, it is best to take it with a meal. It is suggested to space out the intake of Synthroid and iron by 3 to 4 hours. You could take the Synthroid at midday and your multivitamin at dinner time.
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