Using Seroquel for long-term insomnia treatment is generally well tolerated. However, some people may experience increased appetite and weight gain on this medication, while others may develop a tolerance requiring a dosage adjustment. It is important to note that medications for insomnia are typically meant for short-term use. It is recommended to focus on good sleep hygiene practices, such as limiting screen time before bed, establishing a consistent wake-up time, keeping the bedroom for sleep and intimacy only, avoiding clock-watching at night, refraining from napping during the day, and minimizing stimulants like caffeine in the afternoon. In case of difficulty falling asleep, it can be helpful to get out of bed for a short period and return to reset the sleep cycle. Writing down worries before bed can also help ease the mind.