After researching the ingredients in the It Works product line, I cannot confirm that there is no risk of interaction between Effexor (venlafaxine), bupropion and the ingredients. Therefore, I recommend that you pay close attention to the appearance of new side effects or changes in the effectiveness of your antidepressants if you attempt to take the supplement. Additionally, continue to wait several hours between taking the two types of products, which may help reduce the risk of the It Works supplement "sticking" to the antidepressants and eliminating them. Have a nice day.
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