How to manage diarrhea with Plaquenil?

To manage diarrhea while taking Plaquenil, it is suggested to divide the dose and take one tablet twice a day with meals instead of taking both tablets together. This can help reduce the side effect. If the diarrhea persists after two weeks, it is recommended to consult with a pharmacist who can contact your doctor to discuss the possibility of adjusting the dosage. Additionally, it is important to note that the side effect may decrease over time. If you have any further questions, feel free to reach out to a healthcare professional for guidance.