During pregnancy, it's best to avoid taking Advil as it is not recommended during the first and third trimesters, and should only be used with medical advice during the second trimester. Tylenol, on the other hand, is safe to take throughout all trimesters of pregnancy. For relief of headaches, body aches, and other pains during pregnancy, Tylenol is the best and safest choice. If you have any other questions, feel free to ask for more information.