Yes, it is possible to combine Zantac with Omeprozole for reflux during pregnancy. Omeprozole is a good medication for relieving reflux, and combining it with Zantac can provide additional relief if needed. However, there is a risk of developing tolerance to Zantac over time, so it may be necessary to increase the dose for the same level of control. It is recommended to start with a low dose and monitor the results. Non-pharmacological methods can also be helpful in managing reflux symptoms and reducing their frequency.